Sydney researchers have found cancer cells can repair their DNA by using 'cables' in their nucelus. The findings open new possibilities for designing future cancer treatments.
Dec 1, 2020
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SETD2 is a protein well known as a chromatin remodeler, one that helps turn genes on or off by modifying histone proteins in the nucleus of the cell. When researchers discovered that SETD2 is mutated or lost in several cancer ...
Dec 23, 2020
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We've come a long way in cancer treatments – we have powerful, effective drugs for many types of cancer and we're moving toward ever more specific, less invasive therapies. But the problem with cancer is that it's always ...
Aug 27, 2013
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The tumor suppressor p53 does all it can to prevent oncogenes from transforming normal cells into tumor cells by killing defective cells or causing them to become inactive. Sometimes oncogenes manage to initiate tumor development ...
Mar 24, 2014
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When integrins let go of their ligands and the actin cytoskeleton inside the dendritic cell, the activity of another cell surface receptor, the GM-CSF receptor, rises. This increased signaling induces the dendritic cells ...
Oct 29, 2014
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Florida State University researchers led by physics doctoral student Campion Loong have achieved significant benchmarks in a study of the human cardiac protein alpha-tropomyosin, which is an essential, molecular-level component ...
Aug 31, 2012
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Researchers studying a type of cell found in the trillions in our brain have made an important discovery as to how it responds to brain injury and disease such as stroke. A University of Bristol team has identified proteins ...
Jul 25, 2013
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A new study published in Nature Cardiovascular Research uncovers the crucial role of the AmotL2 protein in connecting mechanical forces to endothelial cell integrity and alignment. This discovery sheds light on junctional ...
Jun 30, 2023
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A team of neuroscientists have developed an intervention that normalizes multiple biological functions in mice afflicted with Fragile X Syndrome (FXS). Its breakthrough centers on protein synthesis, or the building of proteins, ...
Nov 7, 2017
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Researchers at the University of Cambridge and the University of Zurich have discovered that a drug newly approved for cancer improves kidney dysfunction in a mouse model of Dent disease 2 and Lowe syndrome
Sep 9, 2020
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