Diseases, Conditions, Syndromes

Physical frailty syndrome: A cacophony of multisystem dysfunction

In the inaugural issue of the journal Nature Aging a research team led by aging expert Linda P. Fried, MD, MPH, dean of Columbia University Mailman School of Public Health, synthesizes converging evidence that the aging-related ...

Immunology

Gut cells sound the alarm when parasites invade

To effectively combat an infection, the body first has to sense it's been invaded, then the affected tissue must send out signals to corral resources to fight the intruder. Knowing more about these early stages of pathogen ...

Medical research

Digging deep for differences in Duchenne muscular dystrophy

A UT Southwestern research team has cataloged gene activity in the skeletal muscle of mice, comparing healthy animals to those carrying a genetic mutation that causes Duchenne muscular dystrophy (DMD) in humans. The findings, ...

Diseases, Conditions, Syndromes

Enhanced scorpion venom molecules can be used to treat Chagas disease

Animal toxins are research targets owing to their therapeutic and biotechnological potential. Researchers at the Federal University of the ABC (UFABC), Federal University of São Paulo (UNIFESP) and Federal University of ...

Neuroscience

An unexpected role for the brain's immune cells

An important part of the brain's immune system, cells called microglia constantly extend and retract "branches" from their cell body to survey their environment. Think of an octopus, not moving its body, but reaching its ...

Oncology & Cancer

CRISPR-edited CAR T cells enhance fight against blood cancers

Knocking out a protein known to stifle T cell activation on CAR T cells using the CRISPR/Cas9 technology enhanced the engineered T cells' ability to eliminate blood cancers, according to new preclinical data from researchers ...

Genetics

Treating brain diseases now possible

Neurological diseases of the brain such as dementia, autism and schizophrenia are now a growing social problem. Nevertheless, studies on their definitive cause are still insufficient. Recently, a POSTECH research team has ...

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