Medications

Peresolimab found to be efficacious for rheumatoid arthritis

Peresolimab, a humanized immunoglobulin G1 monoclonal antibody designed to stimulate the endogenous programmed cell death protein 1 (PD-1) inhibitory pathway, is efficacious for patients with rheumatoid arthritis, according ...

Oncology & Cancer

Researchers discover hidden genetic influence on cancer

In findings with major implications for the genetics of cancer and human health, researchers at Beth Israel Deaconess Medical Center (BIDMC) and two other science teams in New York City and Rome have uncovered evidence of ...

Oncology & Cancer

Big data brings breast cancer research forwards by 'decades'

Scientists have created a 'map' linking the shape of breast cancer cells to genes turned on and off, and matched it to real disease outcomes, which could one day help doctors select treatments, according to a study published ...

Oncology & Cancer

CRISPR-edited CAR T cells enhance fight against blood cancers

Knocking out a protein known to stifle T cell activation on CAR T cells using the CRISPR/Cas9 technology enhanced the engineered T cells' ability to eliminate blood cancers, according to new preclinical data from researchers ...

Neuroscience

'Microlesions' in epilepsy discovered by novel technique

Using an innovative technique combining genetic analysis and mathematical modeling with some basic sleuthing, researchers have identified previously undescribed microlesions in brain tissue from epileptic patients. The millimeter-sized ...

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