Researchers have deciphered a signaling cascade through which inborn errors in metabolism provoke deadly neuroendocrine tumors in the adrenal glands. This discovery explains how impaired metabolism due to mutations in a key ...
Aug 16, 2022
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Findings from a new study at the Marshall University Joan C. Edwards School of Medicine show that a thymidine phosphorylase (TYMP) inhibitor could help slow thrombosis in COVID-19 patients.
Aug 16, 2022
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In many cases of epilepsy—a disorder that disrupts the normal pattern of electrical activity in the brain and often results in seizures—the underlying cause is unknown, according to the National Institute of Neurological ...
Jul 7, 2022
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Let's face it. As enticing as the idea of starting lunch with a chocolate cake might be, few would actually make that choice when it comes down to it. And yet, at the end of the meal, many would reach for that same cake without ...
Jul 6, 2022
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Immune checkpoint inhibitors have revolutionized cancer care. The therapy works by preventing tumors from shutting down the immune response, which in turn allows T cells to kill cancer cells. Established checkpoint inhibitors ...
Jun 27, 2022
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RET is a receptor protein with tyrosine kinase activity that can transfer a phosphate group from ATP to other molecules modifying their shape and function in signaling pathways that are essential to organogenesis and tissue ...
Jun 24, 2022
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Northwestern Medicine investigators recently discovered that the mitochondrial respiratory chain—a series of protein complexes essential for a cellular respiration and energy production—is necessary for the activation ...
May 13, 2022
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Researchers have developed a miniature microscope that is designed for high-resolution 3D images inside the brains of living mice. By imaging deeper into the brain than previously possible with miniature widefield microscopes, ...
Mar 29, 2022
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Under stress, the human heart struggles to pump blood efficiently through the body. Over time, as the heart overexerts itself trying to make up for this lost efficiency, harmful changes take place. The most worrisome of these ...
Mar 15, 2022
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Blocking a protein chain reaction makes childhood leukemia cells more sensitive to an existing targeted treatment, a new study shows. The research is still at an early stage, but the drugs used in the study already exist, ...
Feb 25, 2022
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