Medical research

Key mechanism links exercise to muscle growth

Scientists from King's College London have identified a mechanism by which exercise – or lack of it – controls the growth and loss of muscle mass.

Medical research

SIRT5 regulation of proteins involved in metabolism

The Sirtuin family of protein deacylases has received considerable attention in recent years due to its links to longevity, diabetes, cancer, and metabolic regulation. In a new study published in the Dec. 3rd 2013 issue of ...

Alzheimer's disease & dementia

Enzyme BACE1 may be important in predicting onset of Alzheimer disease

The critical enzyme beta-secretase1 (BACE1) is known to be elevated in brains with sporadic Alzheimer disease (AD). Scientists have now found increased levels of BACE1 in brains with mild cognitive impairment (MCI), suggesting ...

Oncology & Cancer

Secret vulnerabilities of cancer's 'Death Star' protein revealed

Researchers at the Center for Genomic Regulation in Barcelona, Spain, and the Wellcome Sanger Institute near Cambridge, UK, have comprehensively identified the allosteric control sites found in the protein KRAS. These are ...

Oncology & Cancer

The loss of a protein makes 'jump' the tumor to the lymph node

Metastasis is responsible for 90% of deaths in patients with cancer. Understanding the mechanisms responsible for this process is one of the top goals of cancer research. The metastatic process involves a series of steps ...

Medical research

Scientists discover mechanism that could reduce obesity

Approximately 68 percent of U.S. adults are overweight or obese, according to the National Cancer Institute, which puts them at greater risk for developing cancer, cardiovascular disease, diabetes and a host of other chronic ...

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