Neuroscience

New fluorescent protein permanently marks neurons that fire

A new tool developed at the Howard Hughes Medical Institute's Janelia Research Campus lets scientists shine a light on an animal's brain to permanently mark neurons that are active at a particular time. The tool—a fluorescent ...

Medical research

The death marker protein cleans up your muscles after exercise

Researchers at the University of Copenhagen's Department of Nutrition, Exercise and Sports have demonstrated that physical activity prompts a clean-up of muscles as the protein ubiquitin tags onto worn-out proteins, causing ...

Medications

Repurposed drug shows promise for treating cardiac arrhythmias

Ruxolitinib, a drug that is already approved by the U.S. Food and Drug Administration (FDA) for treating certain cancers and skin conditions, is effective at inhibiting CaMKII, a protein kinase linked to cardiac arrhythmias.

Neuroscience

Newly discovered 'switch' plays dual role in memory formation

Researchers at Johns Hopkins have uncovered a protein switch that can either increase or decrease memory-building activity in brain cells, depending on the signals it detects. Its dual role means the protein is key to understanding ...

Medical research

Exercise rescues mutated neural stem cells

CHARGE syndrome is a severe developmental disorder affecting multiple organs. It affects 1 in 8500 newborns worldwide. The majority of patients carry a mutation in a gene called CHD7. How this single mutation leads to the ...

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