In some cancers, including leukemia in children and adolescents, obesity can negatively affect survival outcomes. Obese young people with leukemia are 50% more likely to relapse after treatment than their lean counterparts.
Apr 1, 2021
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Children and young adults who receive CAR T-cell therapy for the most common childhood cancer, acute lymphoblastic leukemia, suffer remarkably fewer relapses and are far more likely to survive when the treatment is paired ...
Apr 1, 2021
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UNC Lineberger Comprehensive Cancer Center researchers have successfully used an experimental safety switch, incorporated as part of a chimeric antigen receptor T-cell (CAR-T) therapy, a type of immunotherapy, to reduce the ...
Mar 4, 2021
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(HealthDay)—Hispanic/Latino (H/L) children with B-cell acute lymphoblastic leukemia (B-ALL) have an increased incidence of IKZF1 deletion and IGH-CRLF2 translocation, according to a letter to the editor published online ...
Feb 19, 2021
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In a new study led by Yale Cancer Center, researchers have discovered a novel metabolic gatekeeper mechanism for leukemia. This mechanism depends on a molecule called PON2, which could lead to a new treatment for the disease. ...
Feb 1, 2021
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St. Jude Children's Research Hospital scientists have identified factors that influence how children with acute lymphoblastic leukemia (ALL) respond to methotrexate. High-dose methotrexate is a part of modern curative therapy ...
Nov 10, 2020
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Cancer remodels the architecture of our chromosomes so the disease can take hold and spread, University of Virginia researchers have revealed.
Oct 27, 2020
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(HealthDay)—If Obamacare, or the Affordable Care Act (ACA), is repealed, pediatric cancer patients could lose critical insurance coverage, a new study warns.
Oct 22, 2020
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(HealthDay)—Contemporary survivors of childhood acute lymphoblastic leukemia (ALL) have reduced late morbidity and mortality, according to a study published online July 24 in the Journal of Clinical Oncology.
Aug 21, 2020
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(HealthDay)—Survivors of adolescent and young adult (AYA) acute lymphoblastic leukemia (ALL) may experience late effects, with a high incidence of subsequent endocrine disease and cardiac disease, according to a study published ...
Jul 31, 2020
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