For the first time, an immunosuppressive agent has shown better organ survival in kidney transplant recipients than a calcineurin inhibitor, the current standard of care, according to a worldwide study led by UC San Francisco ...
Jan 27, 2016
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A limitation of organ transplant is acute rejection of the graft by the host immune system. Graft rejection is mediated by the development of CD8+ cytotoxic T cells that target donor MHC class I molecules, and in animal models, ...
Jan 21, 2016
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University of Manchester researchers have used a new technique to recondition poorly functioning lungs and remove donor white blood cells in an attempt to increase the number of lungs available for transplant, and at the ...
Sep 14, 2015
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Researchers at the Bellvitge Biomedical Research Institute (IDIBELL) and doctors at University Hospital of Bellvitge, together with a team of researchers from the University of California, Cincinnati Children's Hospital, ...
Nov 18, 2014
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Acute rejection after kidney transplantation occurs in about 15%–20% of patients despite immunosuppressive therapy. Rejection is usually heralded by an increase in the patient's serum creatinine (a marker of kidney function), ...
Nov 11, 2014
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Stanford University researchers have devised a noninvasive way to detect heart-transplant rejection weeks or months earlier than previously possible. The test, which relies on the detection of increasing amounts of the donor's ...
Jun 18, 2014
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Among patients with end-stage renal disease undergoing living-related kidney transplants, the use of bone-marrow derived mesenchymal (cells that can differentiate into a variety of cell types) stem cells instead of antibody ...
Mar 20, 2012
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