Oncology & Cancer

Pushing T cells down 'memory lane' may improve cancer therapy

Scientists at St. Jude Children's Research Hospital identified a molecular mechanism that in a preclinical study unlocked the promise of CAR T-cell therapy for treatment of solid tumors. The results were published today in ...

Diseases, Conditions, Syndromes

Dynamics of adaptive immunity in tuberculosis uncovered

Unlike other infectious diseases that affect the lungs, the immune response to fight tuberculosis (TB) infections develops at least twice as slowly. Until recently, the dynamic interplay between bacteria and the host's immune ...

Immunology

Discovery of an innate immunological memory in the intestine

The innate immune system plays a crucial role in regulating host-microbe interactions, and especially in providing protection against pathogens that invade the mucosa. Using an intestinal infection model, scientists from ...

Immunology

T-cell responses in respiratory diseases

Respiratory illnesses are on the rise in an increasingly polluted world. Particularly, viral respiratory infections tend to aggravate previously existing respiratory illnesses, or cause life-long negative after-effects in ...

Immunology

Learning to help the adaptive immune system

Scientists from the Institute of Industrial Science at The University of Tokyo demonstrated how the adaptive immune system uses a method similar to reinforcement learning to control the immune reaction to repeat infections. ...

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