Scientists have discovered that the body's own natural killer cells can suppress the immune benefits of therapeutic vaccines, a problem that can affect inoculations against chronic viral infections and cancer.
In a case study, scientists of the German Center for Infection Research (DZIF) and the University Medical Center Hamburg-Eppendorf investigated the T-cell response of a cancer patient, who was suffering from prolonged COVID-19. ...
Jul 14, 2022
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Human immunodeficiency virus 1, more commonly known as HIV-1, is known for its uncanny ability to evade the immune system. Scientists at Scripps Research and collaborators have now uncovered how our innate immune system—the ...
Jul 8, 2022
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Scientists at St. Jude Children's Research Hospital identified a molecular mechanism that in a preclinical study unlocked the promise of CAR T-cell therapy for treatment of solid tumors. The results were published today in ...
Jun 22, 2022
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Unlike other infectious diseases that affect the lungs, the immune response to fight tuberculosis (TB) infections develops at least twice as slowly. Until recently, the dynamic interplay between bacteria and the host's immune ...
May 17, 2022
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The innate immune system plays a crucial role in regulating host-microbe interactions, and especially in providing protection against pathogens that invade the mucosa. Using an intestinal infection model, scientists from ...
Feb 28, 2022
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Circadian clocks, which regulate most of the physiological processes of living beings over a rhythm of about 24 hours, are one of the most fundamental biological mechanisms. By deciphering the cell migration mechanisms underlying ...
Oct 18, 2021
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Respiratory illnesses are on the rise in an increasingly polluted world. Particularly, viral respiratory infections tend to aggravate previously existing respiratory illnesses, or cause life-long negative after-effects in ...
Oct 1, 2021
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UMass Medical School scientists Katherine A. Fitzgerald, Ph.D.; Fiachra Humphries, Ph.D.; and Liraz Galia, Ph.D., working with the British-based pharmaceutical company GlaxoSmithKline, have identified a novel molecule capable ...
Jun 11, 2021
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Immunity often calls to mind the adaptive immune response, made up of antibodies and T cells that learn to fight specific pathogens after infection or vaccination. But the immune system also has an innate immune response, ...
May 5, 2021
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