Medications

Replication-deficient JYNNEOS recommended for orthopoxvirus

The replication-deficient Vaccinia virus vaccine (JYNNEOS) is recommended over the replication-competent Vaccinia virus vaccine ACAM2000 for individuals with occupational exposure to orthopoxvirus, according to research ...

Surgery

Early tracheostomy no aid for severe stroke outcomes

Early tracheostomy does not significantly improve the rate of survival without severe disability at six months for patients with severe stroke receiving mechanical ventilation, according to a study published online May 4 ...

Medications

Steroids best placebo in high-risk IgA nephropathy

(HealthDay)—Steroids reduce the risk for major adverse kidney outcomes in people with high-risk immunoglobulin A nephropathy (IgAN), but full-dose methylprednisolone increased the risk for serious adverse events, according ...

Diseases, Conditions, Syndromes

Efpeglenatide lowers risk for adverse CV events in T2DM

(HealthDay)—For patients with type 2 diabetes and a history of cardiovascular disease or current kidney disease, the risk for adverse cardiovascular events is lower with efpeglenatide, an exendin-based glucagon-like peptide ...

Obstetrics & gynaecology

Higher-dose DHA in pregnancy tied to fewer early preterm births

(HealthDay)—Supplementation with a higher dose of docosahexaenoic acid (DHA) versus the standard prenatal dose during the second half of pregnancy is associated with a lower rate of early preterm births, according to a ...

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