Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows a recent study. Rather, the formation of protein into liquid droplets may help to dissolve ...
Jul 15, 2024
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In people with a rare condition called light chain amyloidosis, light chain proteins—which are a component of antibodies—mutate and build up in different organs. In new research published in The FEBS Journal, investigators ...
Jul 10, 2024
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Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are two devastating neurodegenerative diseases. Scientists have long suspected a protein called FUS might play a role, but the exact mechanism remained ...
Jun 14, 2024
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Scientists from St Petersburg University and the University of Montpellier have developed the first software enabling the prediction of pairs of proteins in amyloid fibrils capable of co-aggregation, i.e. a process by which ...
Apr 19, 2024
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Ginkgo Diterpene Lactone Meglumine (GDLM), a group of organic compounds that derive from the Ginkgo biloba plant, can improve cognitive function in patients who recently experienced an acute ischemic stroke, according to ...
Mar 14, 2024
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Many neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases, are characterized by the accumulation of protein clumps, or aggregates, in the brain, which has led scientists to assume that the protein tangles ...
Feb 13, 2024
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Studying strange forms of RNA associated with the formation of aggregates in the brains of ALS patients could lead to new avenues for treatments.
Dec 18, 2023
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Neurodegenerative diseases are characterized by the deposition of clumped proteins in the brain and progressive neuronal cell death. Although the causal link between protein aggregates and neurodegeneration is clear, how ...
Dec 4, 2023
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Researchers at the Technical University of Munich (TUM) have developed a method for assessing the number and structure of aggregated blood platelets (or thrombocytes) that can potentially help quantify the risk of a severe ...
Nov 29, 2023
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A mechanism that led some patients to experience cases of deadly clotting following some types of COVID-19 vaccination has been identified in new research.
Oct 30, 2023
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