Oncology & Cancer

Hedgehog pathway key in tamoxifen-resistant breast CA

(HealthDay)—Noncanonical Hedgehog (Hh) signaling is activated in tamoxifen-resistant tumors, and the phosphoinositide 3-kinase inhibitor/protein kinase B (PI3K/AKT) pathway plays a key role protecting Hh signaling molecules, ...

Oncology & Cancer

Socioeconomic disadvantage linked to breast cancer tumor disparity

Racial and ethnic disparities in breast tumor aggressiveness might be explained by social factors that influence the developing tumor and place those in disadvantaged groups at higher risk for aggressive breast cancer, according ...

Oncology & Cancer

Blood hormone levels can predict long-term breast cancer risk

Blood hormone tests can predict a woman's risk for developing postmenopausal breast cancer for up to 20 years, according to a study led by Xuehong Zhang, MD, Channing Division of Network Medicine, Brigham and Women's Hospital ...

Immunology

Mechanism found connecting metastatic breast cancer and arthritis

Working with mouse models, researchers have found a strong connection between autoimmune arthritis and increased aggressiveness in metastatic breast cancer. The connection appears to involve the tendency of autoimmune arthritis ...

Oncology & Cancer

Inhibiting cell migration in breast cancer

(Medical Xpress) -- Scientists from the Friedrich Miescher Institute for Biomedical Research together with colleagues from the University of Fribourg have discovered a signaling mechanism controlling mobility and metastasis ...

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