Immunology

Pathway to resolve allergic asthma is discovered

A group of Brazilian researchers succeeded in preventing allergic asthma from progressing in experimental models by increasing the amount of a certain protein. This increase, in turn, blocked the CD4+ T lymphocytes responsible ...

Immunology

Asthma's androgen connection

Women are more prone to developing asthma, particularly more severe types of asthma, compared to men. Studies have shown that the sex hormones, estrogen and testosterone, influence the mechanisms driving airway inflammation ...

Immunology

Obesity alters airway muscle function, increases asthma risk

New research suggests that obesity changes how airway muscles function, increasing the risk of developing asthma. The study is published ahead of print in the American Journal of Physiology—Lung Cellular and Molecular Physiology.

Inflammatory disorders

Experimental drug targets nucleus of allergen-sensitized cells

Transcription factors, the tiny proteins that switch genes on or off in the nucleus of cells, are considered unreachable molecular targets for drugs attempting to treat medical conditions. Overcoming this challenge, researchers ...

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