Medical research

In the liver, a stressed cell can be bad news for its neighbors

A key protein in the communication channels between cells can allow a stress response in one liver cell to spread to neighboring liver cells in mice, causing otherwise healthy cells to become dysfunctional, according to new ...

Medical research

Could an antibody drug help you shed pounds?

An experimental antibody drug that targets one of the body's key metabolism regulators may help obese people lose weight—at least briefly.

Diseases, Conditions, Syndromes

The gut shields the liver from fructose-induced damage

After one consumes food or a beverage containing fructose, the gastrointestinal system, or gut, helps to shield the liver from damage by breaking down the sugar before it reaches the liver, according to a new multi-center ...

Diseases, Conditions, Syndromes

New imaging method could help detect and monitor liver disease

It's currently difficult to screen for certain liver diseases and to monitor these conditions once they're discovered. A team led by investigators at Massachusetts General Hospital (MGH) and the Massachusetts Institute of ...

Immunology

How a fat cell's immune response makes obesity worse

When obesity occurs, a person's own fat cells can set off a complex inflammatory chain reaction that can further disrupt metabolism and weaken immune response—potentially placing people at higher risk of poor outcomes from ...

Medical research

Glucose acts as a double edged sword on longevity factor SIRT1

Feeding and fasting cycles exert control over metabolism and energy utilization. Aberrations are known to cause metabolic diseases, liver dysfunctions and accelerated aging. Expression and activity of the anti-aging factor ...

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