Immunology

Mitophagy in macrophages is a key step toward pulmonary fibrosis

Idiopathic pulmonary fibrosis is a devastating disease, and recently approved therapies have limited efficacy. Lungs become damaged with fibrotic scarring, and the median length of survival after diagnosis is three to five ...

Diseases, Conditions, Syndromes

Tuberculosis avoids and subverts host immunity

An ancient disease, tuberculosis (TB) continues to be one of the major causes of disability and death worldwide. The recent TB cases in Quebec among the Inuit community has underscored the need to find new avenues to eradicate ...

Immunology

Commensal bacteria help orchestrate immune response in lung

Studies in mice demonstrate that signals from the bacteria that harmlessly—and often beneficially—inhabit the human gastrointestinal tract boost the immune system's ability to kill a major respiratory pathogen, Klebsiella ...

Diseases, Conditions, Syndromes

A breakthrough in tuberculosis research

Often causing no symptoms in carriers of the disease, worldwide tuberculosis (TB) infects eight to ten million people every year, kills two million, and it is highly contagious as it is spread through coughing and sneezing.

Medical research

Gene therapy makes mice breath easier

Researchers from Boston University School of Medicine (BUSM) have discovered a new gene therapy that may prevent the progression of emphysema. The study, which appears on-line in the Journal of Clinical Investigation, describes ...

page 2 from 2