Diseases, Conditions, Syndromes

Scientists discover how tuberculosis hijacks the immune system

Scientists have unlocked a key element in understanding how human lungs fight tuberculosis (TB). They hope their research findings, which were published today in the international peer reviewed journal Immunity, will help ...

Surgery

Researchers discover indicator of lung transplant rejection

Research by scientists at Dignity Health St. Joseph's Hospital and Medical Center's Norton Thoracic Institute was published in the July 12, 2017 issue of Science Translational Medicine titled "Zbtb7a induction in alveolar ...

Immunology

First breath shapes the lung's immune system

The lung is an important interface between the body and the outside environment: with each breath, a surface of roughly 100 square meters exchanges oxygen for carbon dioxide. More than 10,000 liters of air pass adult lungs ...

Immunology

Research paves the way for monocyte-based cell therapy

Researchers from VIB-UGent reveal that adult circulating monocytes that get access to the macrophage niche in the liver or the lung can acquire identical tissue-specific macrophage functions and self-maintenance capacities ...

Medical research

Immunoproteasome inhibits healing function of macrophages

Scientists of Helmholtz Zentrum München, a partner in the German Center for Lung Research (DZL), have observed that the immunoproteasome inhibits the repair function of alveolar macrophages. This opens up new therapeutic ...

Immunology

Mitophagy in macrophages is a key step toward pulmonary fibrosis

Idiopathic pulmonary fibrosis is a devastating disease, and recently approved therapies have limited efficacy. Lungs become damaged with fibrotic scarring, and the median length of survival after diagnosis is three to five ...

Diseases, Conditions, Syndromes

Tuberculosis avoids and subverts host immunity

An ancient disease, tuberculosis (TB) continues to be one of the major causes of disability and death worldwide. The recent TB cases in Quebec among the Inuit community has underscored the need to find new avenues to eradicate ...

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