Scientists of Helmholtz Zentrum München, a partner in the German Center for Lung Research (DZL), have observed that the immunoproteasome inhibits the repair function of alveolar macrophages. This opens up new therapeutic ...
Mar 22, 2016
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Idiopathic pulmonary fibrosis is a devastating disease, and recently approved therapies have limited efficacy. Lungs become damaged with fibrotic scarring, and the median length of survival after diagnosis is three to five ...
Feb 24, 2016
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It is well established that people with cystic fibrosis (CF) have two faulty copies of the CFTR gene, but debate continues on the question of whether certain symptoms of the airway disease are caused by the mutation or if ...
Jan 13, 2016
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Researchers at Children's Hospital Los Angeles and The Saban Research Institute of CHLA have created a dynamic functional mouse model for lung injury repair, a tool that will help scientists explain the origins of lung disease ...
Jul 28, 2015
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An ancient disease, tuberculosis (TB) continues to be one of the major causes of disability and death worldwide. The recent TB cases in Quebec among the Inuit community has underscored the need to find new avenues to eradicate ...
Dec 23, 2014
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Studies in mice demonstrate that signals from the bacteria that harmlessly—and often beneficially—inhabit the human gastrointestinal tract boost the immune system's ability to kill a major respiratory pathogen, Klebsiella ...
Sep 11, 2014
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Researchers at Penn Medicine have discovered that the tumor suppressor gene folliculin (FLCN) is essential to normal lung function in patients with the rare disease Birt-Hogg-Dube (BHD) syndrome, a genetic disorder that affects ...
Apr 10, 2014
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A recent study published in the July issue of the Journal of Immunology helps explain why some humans contract bacterial super-infections like pneumonia with influenza. The research was led by Le Bonheur Pediatrician-in-Chief ...
Jul 22, 2013
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Inflammation, cell division and cell differentiation that occur during skeletal muscle regeneration may provide an ideal environment for the highly malignant tumor, rhabdomyosarcoma to arise. These are the findings from a ...
Feb 22, 2012
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Men who suffer from periodontitis, a disease characterised by inflammation of the gums and damage to the structures that surround and support the teeth, are at greater risk of experiencing erectile dysfunction. Effective ...
Mar 12, 2019
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