Neuroscience

Why the brain swells after liver damage

Liver encephalopathy is one of the diseases that claims most lives worldwide. A Norwegian study has revealed that the disease disturbs vital processes in the brain.

Diseases, Conditions, Syndromes

A specially tailored gut microbiome alleviates hyperammonemia in mice

The microbiome of the human intestine consists of a variety of bacteria that assist in digestion, immune regulation, and other processes that are critical for human health. A subset of these bacteria produces urease, an enzyme ...

Diseases, Conditions, Syndromes

Glycerol phenylbutyrate reduces hepatic encephalopathy events

Phase 2 trial results published in the March issue of Hepatology, a journal of the American Association for the Study of Liver Diseases, suggests the potential for Glycerol Phenylbutyrate (GPB) to reduce hepatic encephalopathy ...

Health informatics

Serum ammonia, hospital mortality linked in ICU cirrhosis patients

For patients with cirrhosis in the intensive care unit (ICU), there is an association between early serum ammonia and hospital mortality, according to a study published online July 20 in Alimentary Pharmacology and Therapeutics.

Medications

Ravicti approved for urea cycle disorders

(HealthDay)—Ravicti (glycerol phenylbutyrate) has been approved by the U.S. Food and Drug Administration to treat certain urea cycle disorders (UCDs) in people 2 years and older.

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