A new study suggests that it is possible to design drugs that can target a type of shape-shifting protein involved in Alzheimer's disease, which was previously thought to be undruggable.
Nov 4, 2020
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30
One of the hallmarks of Alzheimer's disease is the formation of amyloid plaques—sticky clumps of a protein called amyloid beta—that collect between neurons in the brain. Increasingly, however, attention has turned from ...
Nov 2, 2020
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Neurons that regularly remodel are more prone to Alzheimer's disease and die when that remodeling goes awry, a new study suggests. The work is the first to track the progression of Alzheimer's at the genetic and molecular ...
Jun 29, 2020
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Sometimes proteins misfold. When that happens in the human brain, the pileup of misfolded proteins can lead to neurodegenerative diseases like Alzheimer's, Parkinson's and ALS.
May 12, 2020
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Experts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "molecular scissors" of CRISPR/Cas9 to search for new genes related to the neurodegenerative ...
Apr 21, 2020
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Fresh insights into damaging proteins that build up in the brains of people with Alzheimer's disease could aid the quest for treatments.
Dec 10, 2019
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In a search for clues to what may delay or prevent Alzheimer's disease, Johns Hopkins Medicine scientists report that smarter, more educated people aren't protected from the disease, but do get a cognitive "head start" that ...
Jun 11, 2019
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In a new study published in Proceedings of the National Academy of Sciences, researchers from the University of Colorado Denver and Binghamton University are the first to map the molecular structure and dynamics of an aggressive ...
May 17, 2019
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Yale researchers have identified a drinkable cocktail of designer molecules that interferes with a crucial first step of Alzheimer's and even restores memories in mice, they report Jan. 2 in the journal Cell Reports.
Jan 3, 2019
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757
Current thinking about Alzheimer's disease is that neuronal cell death in the brain is to blame for the cognitive havoc caused by the disease. But a new study suggests that neuronal death may actually be a protective reaction ...
Dec 27, 2018
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