Neuroscience

What happens around an Alzheimer plaque?

The brains of people living with Alzheimer's are riddled with plaques: protein aggregates consisting mainly of amyloid beta. Despite decades of research, the real contribution of these plaques to the disease process is still ...

Cardiology

Re-purposed drugs could reverse blood vessel damage in diabetes

Drugs that were developed to treat Alzheimer's Disease could be re-purposed to prevent—or even reverse—the damage done to the blood vessels in people who are obese or suffer from type 2 diabetes, according to new research.

Neuroscience

Plasticity may make neurons vulnerable to Alzheimer's disease

Neurons that regularly remodel are more prone to Alzheimer's disease and die when that remodeling goes awry, a new study suggests. The work is the first to track the progression of Alzheimer's at the genetic and molecular ...

Neuroscience

Pulse pressure: A game changer in the fight against dementia

A recent paper published in Frontiers in Neuroscience, outlines a pulse-pressure-induced pathway of cognitive decline that sheds light on why previous treatments for dementia may have failed and proposes promising new directions ...

Alzheimer's disease & dementia

How toxic protein spreads in Alzheimer's disease

Toxic versions of the protein tau are believed to cause death of neurons of the brain in Alzheimer's disease. A new study published in Nature Communications shows that the spread of toxic tau in the human brain in elderly ...

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