Alzheimer's disease & dementia

Direct toxic action of beta-amyloid identified

Hyperactive neurons in specific areas of the brain are believed to be an early perturbation in Alzheimer's disease. For the first time, a team from the Technical University of Munich (TUM) was able to explain the reasons ...

Alzheimer's disease & dementia

Blood tests for Alzheimer's: Why new studies are encouraging

Many people who have problems with their memory, especially if they are elderly, worry that they have Alzheimer's disease, which afflicts at least 5.5 million people in the U.S. and brings tremendous burdens to families as ...

Neuroscience

A precise look at Alzheimer's proteins

A substance known as amyloid beta protein gets a lot of attention from scientists. Beta amyloid, as it's also called, is a normal brain protein found in everyone, but for an unknown reason it gunks up in the brains of patients ...

Alzheimer's disease & dementia

New Alzheimer therapy passes another important test

The Alzheimer drug candidate PRI-002 developed at Forschungszentrum Jülich has successfully completed Phase I of clinical research involving healthy volunteers. When administered daily over a period of four weeks, the active ...

Neuroscience

Do microglia hold the key to stop Alzheimer's disease?

A Leuven research team led by Prof. Bart De Strooper (VIB-KU Leuven, UK DRI) studied how specialized brain cells called microglia respond to the accumulation of toxic proteins in the brain, a feature typical of Alzheimer's. ...

Neuroscience

How fish brain cells react to Alzheimer's disease

Zebrafish, in contrast to humans, have outstanding regenerative capacities: If brain cells are lost due to illness or injury, they will easily regrow from so-called progenitor cells. With sophisticated methods, researchers ...

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