Neuroscience

How fish brain cells react to Alzheimer's disease

Zebrafish, in contrast to humans, have outstanding regenerative capacities: If brain cells are lost due to illness or injury, they will easily regrow from so-called progenitor cells. With sophisticated methods, researchers ...

Medical research

Alzheimer's study links cholesterol and toxic protein clusters

Cholesterol tremendously increases the toxicity of a peptide implicated in Alzheimer's progression, according to research by scientists in the Department of Biochemistry and Biophysics in Texas A&M's College of Agriculture ...

Medical research

Natural Alzheimer's weapon suggests better treatment

Scientists have shown a molecular chaperone is working like a waste management company to collect and detoxify high levels of toxic amyloid beta peptide found in Alzheimer's disease.

Genetics

Newly found genetic variant defends against Alzheimer's disease

Columbia researchers have discovered a genetic variant that reduces the odds of developing Alzheimer's disease by up to 70% and may be protecting thousands of people in the United States from the disease. The study, "Rare ...

Medical research

Anti-amyloid drugs and Alzheimer's disease

An estimated 50 million people around the world have Alzheimer's disease (AD), and perhaps twice that number are unknowingly "incubating" the disease during its long presymptomatic period. The total cost of caring for AD ...

Alzheimer's disease & dementia

Could a simple smell test help spot Alzheimer's early?

New research suggests that a faltering sense of smell might signal the early stages of Alzheimer's disease, and that an inexpensive, low-tech smell test could spot who needs more extensive screening for dementia.

Neuroscience

Alzheimer's risk genes converge on microglia

DNA determines a large part of the risk for Alzheimer's disease, but it remained unclear how many genetic risk factors contribute to disease. A team led by Prof. Bart De Strooper (VIB-KU Leuven) and Dr. Mark Fiers now show ...

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