On the surface, Parkinson's disease—a neurodegenerative disorder—and melanoma—a type of skin cancer—do not appear to have much in common. However, for nearly 50 years, doctors have recognized that Parkinson's disease ...
Apr 7, 2021
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More than three decades of research on Alzheimer's disease have not produced any major treatment advances for those with the disorder, according to a UCLA expert who has studied the biochemistry of the brain and Alzheimer's ...
Aug 19, 2019
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In a new study published in Proceedings of the National Academy of Sciences, researchers from the University of Colorado Denver and Binghamton University are the first to map the molecular structure and dynamics of an aggressive ...
May 17, 2019
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Scientists have known for years that amyloid fibrils—fibrous, ropelike structures formed by closely linked protein molecules—are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play ...
Apr 20, 2022
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Specific mutations in the protein associated with Parkinson's Disease, in which just one of its 140 building blocks is altered, can make a dramatic difference to processes which may lead to the condition's onset, researchers ...
Aug 29, 2016
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Amyloid fibrils are a type of self-assembled proteins/peptides that take on a stacked sheet-like formation. Amyloid fibril aggregates are known to be a cause of several diseases—including Alzheimer's—and therefore, it ...
Aug 8, 2019
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(Medical Xpress) -- Alzheimer's, the degenerative brain disorder that disrupts memory, thought and behavior, is devastating to both patients and loved ones. According to the Alzheimer's Association, one in eight Americans ...
Jun 27, 2011
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In many neurodegenerative diseases like Parkinson's, protein aggregates form in the brain and are assumed to contribute to neuronal cell death. Yet there exists a cellular defense mechanism that counteracts these aggregates, ...
Nov 11, 2020
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Protein aggregates have been observed in the nerve tissue of patients with Parkinson's disease which consist of individual components (monomers) of the protein α-synuclein which assemble into what are referred to as amyloid ...
Sep 3, 2019
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The pathological process amyloidosis, in which misfolded proteins (amyloids) form insoluble fibril deposits, occurs in many diseases, including Alzheimer disease (AD) and type 2 diabetes mellitus (T2D). However, little is ...
Feb 17, 2015
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