Alzheimer's disease & dementia

New player in Alzheimer's disease pathogenesis identified

Scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) have shown that a protein called membralin is critical for keeping Alzheimer's disease pathology in check. The study, published in Nature Communications, ...

Alzheimer's disease & dementia

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in the March 30 issue of Science ...

Alzheimer's disease & dementia

Inflammatory changes in the brain twenty years before Alzheimer onset

Roughly twenty years before the first symptoms of Alzheimer's disease appear, inflammatory changes in the brain can be seen, according to a new study from Karolinska Institutet published in the medical scientific journal ...

Neuroscience

Study reveals multiple mechanisms may play role in Alzheimer's

(Medical Xpress)—Researchers investigating a known gene risk factor for Alzheimer's disease discovered it is associated with lower levels of beta amyloid—a brain protein involved in Alzheimer's—in cognitively healthy ...

Alzheimer's disease & dementia

Molecular imaging detects signs of Alzheimer's in healthy patients

An arsenal of Alzheimer's research revealed at the Society of Nuclear Medicine's 59th Annual Meeting indicates that beta-amyloid plaque in the brain not only is involved in the pathology of Alzheimer's disease but may also ...

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