Medical research

What are researchers doing to stop dementia?

They are words nobody wants to hear: Alzheimer's disease and dementia. As the population ages, a growing number of older adults gradually lose cherished memories and the ability to think and, ultimately, to perform even the ...

Neuroscience

Stem cells model genetic risk for developing Alzheimer's disease

New research published in Stem Cell Reports has found elevated cholesterol supply from astrocytes to neurons in the model of Alzheimer's disease (AD) brains, suggesting that modulating brain cholesterol could be explored ...

Alzheimer's disease & dementia

Brain tissue inflammation is key to Alzheimer's disease progression

Neuroinflammation is the key driver of the spread of pathologically misfolded proteins in the brain and causes cognitive impairment in patients with Alzheimer's disease, researchers from the University of Pittsburgh School ...

Alzheimer's disease & dementia

Amyloid deposits in eyes provide a peek at Alzheimer's disease risk

Amyloid plaques are protein deposits that collect between brain cells, hindering function and eventually leading to neuronal death. They are considered a hallmark of Alzheimer's disease (AD), and the focus of multiple investigations ...

Neuroscience

Alzheimer's disease may start inside nerve cells

An experimental study from Lund University in Sweden has revealed that the Alzheimer's protein amyloid-beta accumulates inside nerve cells, and that the misfolded protein may then spread from cell to cell via nerve fibers. ...

Alzheimer's disease & dementia

A potential new treatment target for Alzheimer's disease

Like amyloid plaque, the genetic variant APOE4 has long been associated with Alzheimer's disease, but still little is known about the role the gene plays in the disease process.

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