Alzheimer's disease & dementia

A new culprit of cognitive decline in Alzheimer's disease

It has long been known that patients with Alzheimer's disease have abnormalities in the vast network of blood vessels in the brain. Some of these alterations may also contribute to age-related cognitive decline in people ...

Neuroscience

Unraveling the mysteries of multiple sclerosis

Leiden chemists discovered a new mechanism which might explain how multiple sclerosis shifts to a more severe form. Their findings contribute to unraveling the mysterious course of the disease. They have published their findings ...

Alzheimer's disease & dementia

Immune cell defect stimulates Alzheimer's

Defects in the gene TREM2 are linked to increased risk of Alzheimer's disease. The gene is required to activate immune cells called microglia in the brain, which help to eliminate the neurotoxic deposits that are typical ...

Alzheimer's disease & dementia

Study points to new method to deliver drugs to the brain

Researchers at the University of Rochester Medical Center (URMC) have discovered a potentially new approach to deliver therapeutics more effectively to the brain. The research could have implications for the treatment of ...

Alzheimer's disease & dementia

Hypothesis underpinning dementia research 'flawed'

A hypothesis which has been the standard way of explaining how the body develops Alzheimer's Disease for almost 30 years is flawed, according to a University of Manchester biologist.

Alzheimer's disease & dementia

Alzheimer's disease – don't give up on plaque-busting drugs just yet

Alzheimer's disease is associated with a build-up of plaques in the brain called amyloid beta. These plaques are thought to lead to a loss of neurons, which then causes the classic symptoms of the disease – including memory ...

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