The use of carefully chosen animal models often underlies crucial medical advances. A perfect example is provided by the recent demonstration that a known drug, imatinib, can be used to treat a rare but highly aggressive ...
Oct 15, 2012
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Anaplastic large-cell lymphomas (ALCL) are rare cancers of the white blood cells. New research from the international ERIA consortium, led by scientists in Vienna, has now shown that the same signaling pathway is essential ...
Sep 4, 2018
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(Medical Xpress)—A cancer patient from Bolton with a rare form of Non-Hodgkin's Lymphoma is in remission after becoming the first person outside of the US to trial a new cancer drug, Brentuximab Vedotin, led by University ...
Mar 10, 2014
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The anaplastic large cell lymphoma (ALCL) is a type of leukemia that occurs primarily in children and young adults. An international team of researchers with significant involvement of MedUni Wien has now been able to demonstrate ...
Sep 22, 2021
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Approximately one in 20 patients with non-small cell lung carcinoma (NSCLC) has chromosomal aberrations targeting the anaplastic lymphoma kinase (ALK) gene. This has considerable implications for treatment because these patients ...
Dec 12, 2012
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The drug ceritinib (trade name: Zykadia) has been approved since May 2015 for the treatment of adults with non-small cell lung cancer (NSCLC). It is an option when certain changes in the cancer cells (anaplastic lymphoma ...
Oct 6, 2015
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Anaplastic large cell lymphoma, a form of non-Hodgkin lymphoma, is the most common aggressive lymphoma in children. Chemotherapy and radiation fail to cure about 30% of cases. When tumors are driven by the oncogene ALK—which ...
Aug 3, 2023
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A general problem encountered in cancer therapy is that many patients develop resistance to a drug over the course of treatment. In the case of the blood cancer anaplastic large cell lymphoma (ALCL), an international team ...
Jul 15, 2020
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Personalized medicine in lung cancer relies on the identification and characterization of cancer biomarkers and the availability of accurate detection systems and therapies for those biomarkers. The standard procedure for ...
Jul 1, 2013
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