Diseases, Conditions, Syndromes

Study examines use of drugs to strengthen bones for men receiving ADT

Although some guidelines recommend use of bisphosphonates (a class of drugs used to strengthen bone) for men on androgen deprivation therapy, an analysis finds that prescriptions for these drugs remains low, even for those ...

Oncology & Cancer

Popular prostate cancer therapy may be harmful

A widely used treatment for prostate cancer may cause more harm than good for some patients, according to Dr. Oliver Sartor, medical director of the Tulane Cancer Center.

Diabetes

Androgen receptor signaling tied to insulin resistance

(HealthDay)—Mouse models show tissue-specific androgen receptor (AR) signaling is involved in regulation of metabolism, which may explain the link between androgen deprivation therapy (ADT) and the development of metabolic ...

Oncology & Cancer

ASCO: No benefit for immediate ADT after PSA-only relapse

(HealthDay)—For men with a prostate-specific antigen (PSA)-only-based relapse after prostate surgery or radiation therapy, there seems to be little or no survival benefit for immediate initiation of androgen deprivation ...

Oncology & Cancer

Study identifies a key cellular pathway in prostate cancer

Mayo Clinic researchers have shed light on a new mechanism by which prostate cancer develops in men. Central to development of nearly all prostate cancer cases are malfunctions in the androgen receptor—the cellular component ...

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