Oncology & Cancer
New blood test predicts who will benefit from targeted prostate cancer treatments
A new blood test could predict which men with advanced prostate cancer will respond to new targeted treatments for the disease.
May 3, 2017
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Page 8 - News tagged with androgen receptor
Oncology & Cancer
Study uncovers an additional strategy for targeting treatment-resistant prostate cancer
Prostate cancer cells depend on signaling through the androgen receptor (AR) to grow and survive. Many anti-cancer therapies that target ARs are initially successful in patients, including a class of drugs known as CYP17A1 ...
May 2, 2017
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Oncology & Cancer
PROTAC shows efficacy against castration-resistant prostate cancer in preclinical studies
An orally bioavailable androgen receptor PROTAC, developed using a protein degradation technology, was effective in lowering tumor burden in mice bearing human castration-resistant prostate cancer, according to data presented ...
Apr 5, 2017
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Medical research
Androgen plays key role in ovarian development
Scientists have discovered that the male androgen hormone is an important element in the ovarian development of female chicken embryos, more so than in the development of male testes.
Mar 23, 2017
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Oncology & Cancer
Gene mutation found to drive prostate cancer subtype
A newly discovered genetic mutation that is found in a subtype of prostate cancer is integral to the disease's development and growth, according to research from Weill Cornell Medicine scientists. Their findings could pave ...
Mar 14, 2017
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Oncology & Cancer
Castration-resistant prostate cancer cell growth impeded by endostatin
Failure of hormone deprivation therapy, which is used to slow prostate cancer in patients, leads to castration-resistant prostate cancer, a lethal form of advanced disease with limited treatment options.
Mar 10, 2017
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Oncology & Cancer
Researchers find a new human androgen receptor structure, key target for the treatment of prostate cancer
A research team has studied for the first time the 3-D structure of the homodimeric androgen receptor ligand-binding domain, a structure that eluded researchers for years. This new structure of the nuclear receptor explains ...
Feb 7, 2017
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Oncology & Cancer
New imaging method can detect, monitor and guide treatment for, prostate cancer
An international group of researchers report success in mice of a method of using positron emission tomography (PET) scans to track, in real time, an antibody targeting a hormone receptor pathway specifically involved in ...
Nov 30, 2016
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Oncology & Cancer
Identification of gene defects helps the treatment of prostate cancer
The current method of treating prostate cancer involves identifying gene defects, which could help with the diagnosis of cancer and the development of individualised cancer treatments for patients. Professor Tapio Visakorpi ...
Nov 4, 2016
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Diseases, Conditions, Syndromes
Serendipitous finding leads scientists to propose mechanism to explain benign prostatic hyperplasia
Benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate, affects about half the men between 51 and 60 years of age, and nine out of 10 men older than 80. How BPH happens, however, is still open for ...
Sep 1, 2016
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