For the first time, researchers examine the effects of gender-affirming androgen therapy on breast tissue in transgender men with single-cell resolution. Their results give an unprecedented look into the changes that occur ...
Mar 8, 2023
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(HealthDay)—Hormone therapy for prostate cancer might dramatically increase a man's risk of developing Alzheimer's disease, a large-scale analysis of health data suggests.
Dec 8, 2015
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(HealthDay)—For men with metastatic prostate cancer (mPCa), overall survival (OS) is improved for those treated with androgen deprivation therapy (ADT) and prostate radiotherapy (RT), compared with ADT alone, according ...
Jun 27, 2016
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An orally bioavailable androgen receptor PROTAC, developed using a protein degradation technology, was effective in lowering tumor burden in mice bearing human castration-resistant prostate cancer, according to data presented ...
Apr 5, 2017
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A new study has found that certain prostate cancer medications are linked with an increased risk of dying from heart-related causes in men with congestive heart failure or prior heart attacks. Published in BJU International, ...
Oct 29, 2014
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In a study published in Cell Reports Medicine, a group of Chinese scientists revealed the oncometabolite role of progesterone in advanced prostate cancer and strategies to eliminate its oncogenic effect as an aspect of prostate ...
Mar 15, 2022
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The Endocrine Society today issued a Clinical Practice Guideline (CPG) advising against the use of testosterone therapy in healthy women.
Oct 3, 2014
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Scientists at Memorial Sloan Kettering Cancer Center (MSK) have glimpsed never-before-seen details of the human androgen receptor—the protein inside of cells that responds to male-typical hormones like testosterone. Their ...
Apr 20, 2022
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Recent research from the University of Eastern Finland sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer, showing that the development of drug resistance could be prevented by ...
Apr 10, 2024
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A protein variant common in malignant bladder tumor cells may serve as a new avenue for treating bladder cancer. A multi-institution study led by UC Davis Comprehensive Cancer Center researchers found that targeting androgen ...
Apr 28, 2021
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