A team of physicians and laboratory scientists has taken a key step toward a cure for sickle cell disease, using CRISPR-Cas9 gene editing to fix the mutated gene responsible for the disease in stem cells from the blood of ...
Oct 12, 2016
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Some genetic diseases persist for generation after generation because the genes that cause them can benefit human health.
Oct 5, 2016
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Like jewels in a vault, our precious genetic material is stored in the nucleus of a cell—sequestered away from potentially damaging cellular components and toxins so that no harm can come to it. Yet over the course of a ...
Apr 12, 2016
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Researchers at Harvard Medical School and Dana-Farber Cancer Institute report that humans have a surprisingly high number of genes in which one of two copies has been randomly silenced. They suggest that the phenomenon is ...
Feb 4, 2016
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Researchers have identified a molecular target and experimental treatment strategy for DNA repair defects behind Fanconi anemia - a complex genetic disorder responsible for birth anomalies, organ damage, anemia and cancer.
Jan 12, 2016
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Practically everyone gets fatter as they get older, but some people can blame their genes for the extra padding. Researchers have shown that two different mutations in a gene called ankyrin-B cause cells to suck up glucose ...
Jul 13, 2015
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Each year, between 25 and 35 children in the United States and Canada are diagnosed with an inherited bone marrow failure syndrome called Diamond Blackfan anemia (DBA), according to the US Centers for Disease Control and ...
May 11, 2015
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In a study just published in the journal Nature, scientists at the Deutsches Krebsforschungszentrum Heidelberg and at the Institute for Stem Cell Technology and Experimental Medicine have uncovered that environmental stress ...
Feb 18, 2015
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Many rare disorders are caused by gene mutation, like sickle cell anemia. Yet until now the underlying genetic cause of more common conditions – for example, rheumatoid arthritis – has evaded scientists for years.
Dec 20, 2013
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Researchers at Whitehead Institute have identified a protein that is the target of glucocorticoids, the drugs that are used to increase red blood cell production in patients with certain types of anemia, including those resulting ...
Jun 9, 2013
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