Diseases, Conditions, Syndromes

A better treatment for sickle cell disease

Sickle cell disease is the most prevalent inherited blood disorder in the world, affecting 70,000 to 100,000 Americans. However, it is considered an orphan disease, meaning it impacts less than 200,000 people nationally, ...

Diseases, Conditions, Syndromes

New molecular mechanisms identified in chronic skin inflammation

Frequently occurring chronic skin inflammation like in atopic dermatitis (AD or neurodermatitis) and psoriasis have different causes such as genetic predisposition, stress or allergens. These frequently occurring skin diseases ...

Medical research

SARS-CoV-2 mutations in competition

Prior to the emergence of new mutants of the coronavirus, such as the British variant B.1.1.7, the SARS-CoV-2 variant named D614G had already mutated from the original SARS-CoV-2 pathogen that triggered the pandemic. D614G ...

Genetics

Researchers discover a rare genetic form of dementia

A new, rare genetic form of dementia has been discovered by a team of Penn Medicine researchers. This discovery also sheds light on a new pathway that leads to protein build up in the brain—which causes this newly discovered ...

Neuroscience

Scientists capture diversity in the 'stars' of our nervous system

Scientists at the Francis Crick Institute have found that the location of astrocytes in the brain and spinal cord, may affect their role in maintaining the body's nervous system. This discovery could help scientists uncover ...

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