Medical research

Double trouble for drug-resistant cancers

ETC-159, an anti-cancer drug that is currently in early phase clinical trials for use in a subset of colorectal and gynecological cancers, could also prevent some tumors from resisting therapies by blocking a key DNA repair ...

Oncology & Cancer

Spontaneous cell fusions amplify genetic diversity within tumors

Evolution within groups of tumor cells follows the principles of natural selection, as evolution in pathogenic microbes. That is, the diversity of cellular characteristics within a group leads to differences in the ability ...

Oncology & Cancer

Anti-depressant repurposed to treat childhood cancer

A new study has found that a commonly prescribed antidepressant may halt growth of a type of cancer known as childhood sarcoma, at least in mice and laboratory cell experiments. The findings, from researchers at Karolinska ...

Oncology & Cancer

Revealed: How cancer develops resistance to treatment

Cancer cells can turn on error-prone DNA copy pathways to adapt to cancer treatment, a breakthrough study published in the journal Science has revealed. Bacteria use the same process, termed stress-induced mutagenesis, to ...

Medical research

Suspect cells' 'neighbor' implicated in colorectal cancer

Colorectal cancer kills more than 50,000 people a year in the United States alone, but scientists have struggled to find the exact mechanisms that trigger the growth of tumors in the intestine.

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