Protein Kinase C (PKC) enzymes are crucial for a number of cellular activities, including cell survival, proliferation and migration—functions that must be carefully controlled lest cells get out of control and form a tumor. ...
Mar 20, 2019
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333
The development of effective anti-androgen therapies for prostate cancer is a major scientific advance. However, some men who receive these targeted treatments are more likely to develop a deadly treatment-resistant prostate ...
Feb 28, 2019
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36
When women or men receive the worrisome diagnosis of breast cancer, that news comes with an important piece of information, namely, whether their cancer is HER2-positive or HER2-negative. It can be especially difficult to ...
Feb 7, 2019
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40
Regular use of a common type of medication, such as aspirin and ibuprofen, significantly improves survival for a third or more patients with head and neck cancer, a new study led by UC San Francisco has found.
Jan 25, 2019
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157
By connecting highly effective cancer immunotherapy drugs such as anti-CTLA4 (ipilimumab) and anti-PD-L1 (atezolizumab) to peptides that bind to tissues in and around tumors, a research team based at the University of Chicago ...
Nov 8, 2017
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Albert Einstein College of Medicine researchers report that the composition of people's gut bacteria may explain why some of them suffer life-threatening reactions after taking a key drug for treating metastatic colorectal ...
Nov 1, 2017
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MYC is a regulator gene. It controls the expression of other genes and codes transcription factors or proteins involved in many fundamental cellular processes. It's also among the most frequently altered genes found in cancer, ...
Feb 1, 2017
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Cancer researchers have long observed the value of treating patients with combinations of anti-cancer drugs that work better than single drug treatments. Now, in a new study using laboratory-grown cells and mice, Johns Hopkins ...
Aug 24, 2016
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84
Many types of leukemia are caused by loss of enzymes such as Pten, which normally keeps cell growth in check, or conversely, the over-activation of enzymes that normally enhance cell proliferation, such as Shp2. Some anti-leukemia ...
Oct 13, 2015
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37
Despite extraordinary advances in new drugs and biotechnology, cancer is still one of the leading causes of death worldwide.
May 25, 2015
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