Oncology & Cancer

Knockout of CD5 on CAR T cells shown to boost anti-tumor efficacy

The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, ...

Medications

Simplified antibiotic may set the stage for antitumor treatments

Garden soil houses a variety of bacteria and their natural byproducts—including one that may help halt tumor growth. Lankacidins are molecules that can be isolated from Strepomyces rochei, a common bacterium in soil. In ...

Oncology & Cancer

Novel molecules offer hope to pancreatic cancer patients

EU researchers have made significant progress along the road to delivering novel drugs that improve life expectancy and the quality of life of pancreatic cancer patients. Following a systematic screening of natural and chemically ...

Oncology & Cancer

New therapeutic target for prostate cancer identified

A small, naturally occurring nucleic acid sequence, called a microRNA, known to regulate a number of different cancers, appears to alter the activity of the androgen receptor, which plays a critical role in prostate cancer. ...

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