Oncology & Cancer

CAR macrophages go beyond T cells to fight solid tumors

Chimeric antigen receptor (CAR) T cell therapy has been a game-changer for blood cancers but has faced challenges in targeting solid tumors. Now researchers from the Perelman School of Medicine at the University of Pennsylvania ...

Obstetrics & gynaecology

Designing an emergency stop switch for immunotherapies

Immunotherapy, unlike chemotherapy and radiotherapy, arms the body's immune system to attack cancer cells. In recent years, it has proven to be remarkably successful at treating leukemia, lymphoma and other liquid cancers, ...

Oncology & Cancer

Engineering the immune system to tackle glioblastoma

Each year, roughly 15,000 Americans are diagnosed with Glioblastoma Multiforme (GBM), the most common malignant primary brain tumor in adults, and also the most lethal. Surgery, radiation, and chemotherapy can help slow the ...

Oncology & Cancer

Drug-light combo could offer control over CAR T-cell therapy

Bioengineers at the University of California San Diego are a step closer to making CAR T-cell therapy safer, more precise and easy to control. They developed a system that allows them to select where and when CAR T cells ...

Oncology & Cancer

Scientist designs 'express courier service' for immune cells

Immunotherapy is a promising cancer treatment that uses genetically modified immune cells to fight cancer. It can be used as a primary treatment or in combination with other treatments such as radiation and chemotherapy to ...

Oncology & Cancer

Super-powered immune cells

The phase 1 clinical trial will test the feasibility and safety of CAR-T cells—genetically modified white blood cells harvested from a patient's own blood with the unique ability to directly attack and kill cancers—to ...

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