HIV & AIDS

Researchers make first steps toward a cure for HIV

Researchers have developed a way to pull HIV out of the latent reservoir making the virus visible to the immune system and providing the potential to be killed by treatment.

HIV & AIDS

Existing drugs may limit damage caused by HIV

Yale researchers have identified four drugs that may help minimize the long-term health effects of HIV infection, they report June 23 in the Journal of Clinical Investigation.

Medications

Fostemsavir active in multidrug-resistant HIV-1 infection

(HealthDay)—Amongpatients with multidrug-resistant HIV-1 infection who have limited therapy options, reductions in HIV-1 RNA level were significantly greater in those who received fostemsavir compared with placebo during ...

HIV & AIDS

Immunotherapy combo achieves reservoir shrinkage in HIV model

Stimulating immune cells with two cancer immunotherapies together can shrink the size of the viral "reservoir" in SIV-infected non-human primates treated with antiviral drugs, researchers have concluded. The reservoir includes ...

Diseases, Conditions, Syndromes

Coronavirus: Three lessons from the AIDS crisis

As my governor closes all the public schools and public libraries here in Seattle, I'm thinking about 1981—the year when newspapers in New York and Los Angeles reported that a strange new virus was killing healthy young ...

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Antiretroviral drug

Antiretroviral drugs are medications for the treatment of infection by retroviruses, primarily HIV. When several such drugs, typically three or four, are taken in combination, the approach is known as highly active antiretroviral therapy, or HAART. The American National Institutes of Health and other organizations recommend offering antiretroviral treatment to all patients with AIDS. Because of the complexity of selecting and following a regimen, the severity of the side effects and the importance of compliance to prevent viral resistance, however, such organizations emphasize the importance of involving patients in therapy choices and recommend analyzing the risks and the potential benefits to patients without symptoms.

There are different classes of antiretroviral drugs that act at different stages of the HIV life cycle.

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