HIV & AIDS

Naltrexone implant helps HIV patients prevent opioid relapse

(HealthDay)—Slow-release implantable naltrexone is associated with better outcomes than the oral drug for HIV-positive patients with an opioid addiction, according to a study published in the April issue of The Lancet HIV.

HIV & AIDS

HIV latency differs across tissues in the body

Mechanisms that govern HIV transcription and latency differ in the gut and blood, according to a study published November 15 in the open-access journal PLOS Pathogens by Steven Yukl of San Francisco Veterans Affairs Medical ...

HIV & AIDS

New drug capsule may allow weekly HIV treatment

Researchers at MIT and Brigham and Women's Hospital have developed a capsule that can deliver a week's worth of HIV drugs in a single dose. This advance could make it much easier for patients to adhere to the strict schedule ...

HIV & AIDS

Rising levels of HIV drug resistance

HIV drug resistance is approaching and exceeding 10% in people living with HIV who are about to initiate or reinitiate first-line antiretroviral therapy, according to the largest meta-analysis to date on HIV drug resistance, ...

Diseases, Conditions, Syndromes

HIV drug resistance is threatening gains of treatment

(HealthDay)—Resistance to antiretroviral therapy (ART) is threatening the recent gains of treatment in the rate of new HIV infections, according to a perspective article published online Oct. 25 in the New England Journal ...

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Antiretroviral drug

Antiretroviral drugs are medications for the treatment of infection by retroviruses, primarily HIV. When several such drugs, typically three or four, are taken in combination, the approach is known as highly active antiretroviral therapy, or HAART. The American National Institutes of Health and other organizations recommend offering antiretroviral treatment to all patients with AIDS. Because of the complexity of selecting and following a regimen, the severity of the side effects and the importance of compliance to prevent viral resistance, however, such organizations emphasize the importance of involving patients in therapy choices and recommend analyzing the risks and the potential benefits to patients without symptoms.

There are different classes of antiretroviral drugs that act at different stages of the HIV life cycle.

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