Neuroscience

Alzheimer's risk gene undermines insulation of brain's 'wiring'

It's well known that carrying one copy of the APOE4 gene variant increases one's risk for Alzheimer's disease threefold and two copies about tenfold, but the fundamental reasons why and what can be done to help patients remain ...

Neuroscience

Stem cells model genetic risk for developing Alzheimer's disease

New research published in Stem Cell Reports has found elevated cholesterol supply from astrocytes to neurons in the model of Alzheimer's disease (AD) brains, suggesting that modulating brain cholesterol could be explored ...

Alzheimer's disease & dementia

A potential new treatment target for Alzheimer's disease

Like amyloid plaque, the genetic variant APOE4 has long been associated with Alzheimer's disease, but still little is known about the role the gene plays in the disease process.

Genetics

Decoding the genetics that drive disease

From Alzheimer's to obesity, life can change dramatically if you discover you have a genetic risk of disease. Now, a new study from the Australian Centre for Precision Health, University of South Australia is challenging ...

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