Genetics
Mutant gene stops at-risk people from getting Alzheimer's: Could it lead to treatment?
The APOE4 gene is the most powerful genetic factor driving a person's risk for developing late-onset Alzheimer's disease.
Jun 1, 2022
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News tagged with apoe gene
Psychology & Psychiatry
Gene variant may increase psychiatric risk after traumatic brain injury
A variant of the APOE gene may be linked to worse psychiatric symptoms in people who have had a traumatic brain injury, found a Veterans Affairs San Diego Healthcare System study. Study participants with both the gene variant ...
May 14, 2018
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Neuroscience
Study finds path for addressing Alzheimer's blood-brain barrier impairment
By developing a lab-engineered model of the human blood-brain barrier (BBB), neuroscientists at MIT's Picower Institute for Learning and Memory have discovered how the most common Alzheimer's disease risk gene causes amyloid ...
Jun 8, 2020
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Genetics
Gene variant may help protect against Alzheimer's disease
A new study led by investigators at Massachusetts General Hospital (MGH), in collaboration with the University of Antioquia, Schepens Eye Research Institute of Mass. Eye and Ear, and Banner Alzheimer's Institute, provides ...
Nov 4, 2019
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Alzheimer's disease & dementia
Spinal fluid of people with Alzheimer's risk gene signals inflammation
People who have a gene variant associated with an increased risk of developing Alzheimer's disease also tend to have changes in the fluid around their brain and spinal cord that are detectable years before symptoms arise, ...
Feb 11, 2021
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Alzheimer's disease & dementia
A potential new treatment target for Alzheimer's disease
Like amyloid plaque, the genetic variant APOE4 has long been associated with Alzheimer's disease, but still little is known about the role the gene plays in the disease process.
Jun 14, 2021
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Neuroscience
Risk genes for Alzheimer's and mental illness linked to brain changes at birth
Some brain changes that are found in adults with common gene variants linked to disorders such as Alzheimer's disease, schizophrenia, and autism can also be seen in the brain scans of newborns.
Jan 2, 2013
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Genetics
Genetics study finds ancestral background can affect Alzheimer's disease risk
Genetics contributes to the risk of developing Alzheimer's disease, and the APOE gene is the strongest genetic risk factor, specifically the APOE4 allele. However, it has been known for a while that the risk due to the APOE4 ...
Feb 4, 2021
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Alzheimer's disease & dementia
Study finds key Alzheimer's gene (APOE) acts differently in Caribbean Hispanics
Researchers looking to unlock the mysteries of Alzheimer's disease have revealed new insights from old variants.
Nov 8, 2019
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Genetics
Alzheimer's risk gene disrupts endocytosis, but another disease-linked gene could help
In a new study, a team of scientists based at The Picower Institute for Learning and Memory at MIT and the Whitehead Institute for Biomedical Research reveals evidence showing that the most prominent Alzheimer's disease risk ...
Oct 6, 2020
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