Many medical issues affect nerves, from injuries in car accidents and side effects of chemotherapy to glaucoma and multiple sclerosis. The common theme in these scenarios is destruction of nerve axons, the long wires that ...
May 9, 2013
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A team led by scientists at The Scripps Research Institute has discovered key elements of a strategy commonly used by tumor cells to survive when they spread to distant organs. The finding could lead to drugs that could inhibit ...
Jan 26, 2012
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Challenging a half-century-old theory about why chemotherapy agents target cancer, scientists at Dana-Farber Cancer Institute have devised a test that can predict how effective the drugs will be by determining whether a patient's ...
Oct 27, 2011
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The enzyme caspase-8 induces a molecular cell death programme called pyroptosis without involving its enzymatic activity, a new study by Hamid Kashkar published in Nature shows. In order to safeguard healthy and functioning ...
Nov 26, 2019
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Cancer cells are characterised by the ability to evade apoptosis, a type of programmed cell death that allows the organism to remove damaged cells. Many studies devoted to new chemotherapy treatments aim to induce apoptosis ...
Apr 17, 2019
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Cell death is an important aspect of tissue homeostasis, as well as inflammation and disease pathogenesis related to infection, injury, and tumor growth. Tumor necrosis factor-α (TNFα) coordinates cell death in a variety ...
Jan 17, 2019
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A highly detailed study of how the roundworm C. elegans forms oocytes suggests that the egg-making process leads to the formation and subsequent destruction of cells with an extra nucleus, but that some cellular materials ...
Jul 19, 2018
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Structural biologists at St. Jude Children's Research Hospital have discovered how a key protein functions to trigger cell's suicide machinery, called apoptosis. The scientists found that the protein, called BOK, is controlled ...
May 17, 2018
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Despite many successes in treating pediatric cancer, young children remain at high risk for developing severe, long-lasting impairments in their brain, heart, and other vital organs from chemotherapy and radiation treatments. ...
Dec 22, 2016
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Billions of cells in our bodies die every day in an important process called apoptosis. Now, researchers at the RIKEN Brain Science Institute have mapped out a sequence of events that are necessary for apoptosis to occur ...
Dec 20, 2016
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