Diseases, Conditions, Syndromes

Hemochromatosis mutation linked to other morbidity

(HealthDay)—HFE p.C282Y homozygosity, the most common gene mutation causing hereditary hemochromatosis (type 1), is associated with other morbidity in men and women, according to a study published online Jan. 16 in The ...

Cardiology

Chest CT can ID respiratory AE risk in RA patients on biologics

(HealthDay)—Chest computed tomography (CT) findings may identify risk factors for respiratory adverse events (RAEs) in rheumatoid arthritis (RA) patients undergoing long-term biological therapy, according to a study recently ...

Neuroscience

Gene variant found in brain complicit in MS onset

Multiple sclerosis (MS) is an autoimmune disease affecting the function of the central nervous system. Up to now, most of the 230 genetic variants associated with the disease have been linked to changes in immune cells. However, ...

Arthritis & Rheumatism

Phone-based intervention aids rheumatoid arthritis care

(HealthDay)—A nurse-based phone education intervention can promote shared decision making in patients with newly diagnosed rheumatoid arthritis (RA), according to a study published online Dec. 5 in Musculoskeletal Care.

Arthritis & Rheumatism

Higher cardiovascular risk seen with psoriatic arthritis

(HealthDay)—Cardiovascular risk should be carefully evaluated in patients with psoriatic arthritis, according to a study published online Nov. 5 in the International Journal of Rheumatic Diseases.

Arthritis & Rheumatism

Children with arthritis lack vitamin D

In an analysis of global research, we recently found that children with the most frequent type of arthritis, juvenile idiopathic arthritis (JIA), have abnormally low vitamin D blood levels. We also found that those living ...

Arthritis & Rheumatism

Patchy distribution of joint inflammation resolved

Chronic inflammatory rheumatic diseases such as rheumatoid arthritis (RA) and spondylo-arthritis (SpA) are chronic, disabling diseases with a poor outcome for loco-motoric function if left untreated. RA and SpA each affect ...

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Arthritis

Arthritis (from Greek arthro-, joint + -itis, inflammation; plural: arthritides) is a group of conditions involving damage to the joints of the body.

There are different forms of arthritis and each has a different cause. The most common form of arthritis, osteoarthritis (degenerative joint disease) is a result of trauma to the joint, infection of the joint, or age. Other arthritis forms are rheumatoid arthritis and psoriatic arthritis, autoimmune diseases in which the body attacks itself. Septic arthritis is caused by joint infection. Gouty arthritis is caused by deposition of uric acid crystals in the joint, causing inflammation. There is also an uncommon form of gout caused by the formation of rhomboid crystals of calcium pyrophosphate. This gout is known as pseudogout.

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