Autism spectrum disorders

A common medication restores social deficits in autism mouse model

Reducing the function of the autism-associated gene Pcdh10 leads to impairments in social behavior, according to a study published in Biological Psychiatry. Reducing Pcdh10 function also disrupted the structure and function ...

Genetics

Mutations in life's 'essential genes' tied to autism

Genes known to be essential to life—the ones humans need to survive and thrive in the womb—also play a critical role in the development of autism spectrum disorder (ASD), suggests a new study from Penn Medicine geneticists ...

Genetics

Shared epigenetic changes underlie different types of autism

Individuals with both rare and common types of autism spectrum disorder share a similar set of epigenetic modifications in the brain, according to a study published November 17 in Cell. More than 68% of individuals with different ...

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