Immunology

Common denominator that triggers asthma in favorable environments

In recent decades, asthma has become a major public health problem. The exponential increase in asthma cases in industrialized countries over the past 50 years is due to major changes in the environment. Among these environmental ...

Diseases, Conditions, Syndromes

Three-in-one inhaler helps asthmatics breathe easy

Patients with severe asthma which is not controlled with standard treatment—leaving them at risk of severe asthma attacks—could benefit from using a single inhaler combining three, instead of two therapies, according ...

Diseases, Conditions, Syndromes

Exploring the dietary drivers of asthma

Asthma is a relatively common condition which is not completely understood and remains difficult to comprehensively prevent and treat.

Immunology

CDC: Asthma visit rates decreased from 2001 to 2016

(HealthDay)—Asthma is a common reason for physician visits, although the rate of asthma visits decreased from 2001 through 2016, according to a report published Sept. 20 by the U.S. Centers for Disease Control and Prevention ...

page 1 from 23

Asthma

Asthma is a chronic inflammation of the lungs in which the airways (bronchi) are reversibly narrowed. Asthma affects 7% of the population, and 300 million worldwide. During attacks (exacerbations), the smooth muscle cells in the bronchi constrict, and the airways become inflamed and swollen. Breathing becomes difficult, and asthma causes 4,000 deaths a year in the U.S. Attacks can be prevented by avoiding triggering factors and by drug treatment. Drugs are used for acute attacks, commonly inhaled β2-agonists. In more serious cases, drugs are used for long-term prevention, starting with inhaled corticosteroids, and then long-acting β2-agonists if necessary. Leukotriene antagonists are less effective than corticosteroids but have no side effects. Monoclonal antibodies such as mepolizumab and omalizumab are sometimes effective. Prognosis is good with treatment.

In contrast to chronic obstructive pulmonary disease and chronic bronchitis, the inflammation of asthma is reversible. In contrast to emphysema, asthma affects the bronchi, not the alveoli.

The National Heart, Lung and Blood Institute defines asthma as a common chronic disorder of the airways characterized by variable and recurring symptoms, airflow obstruction, bronchial hyperresponsiveness (bronchospasm), and an underlying inflammation.

Public attention in the developed world has recently focused on asthma because of its rapidly increasing prevalence, affecting up to one in four urban children.

This text uses material from Wikipedia, licensed under CC BY-SA