By studying nerve and liver cells grown from patient-derived induced pluripotent stem cells (iPSCs), Whitehead Institute researchers have identified a potential dual-pronged approach to treating Niemann-Pick type C (NPC) ...
May 15, 2014
0
0
Effective combination therapies are urgently needed to treat triple-negative breast cancer (TNBC), which is insensitive to the existing treatment regimens. However, the synergistic potency of traditional small-molecule combinations ...
Apr 12, 2022
0
3
A new approach to combatting tuberculosis would take advantage of a complex, natural process called autophagy that the human body uses to recycle nutrients, remove damaged cell components, eliminate invading bacteria, and ...
Apr 15, 2015
0
3
In a recent study, scientists led by Professor Stefan Müller from Goethe University's Institute of Biochemistry II investigated a specific form of blood cancer known as acute myeloid leukemia, or AML. The disease mainly ...
Dec 4, 2023
0
15
A greater focus on autophagic activity and metabolism in cancerous cells could make a significant difference in the development of more effective cancer treatments, researchers contend.
Jul 30, 2014
0
0
Boosting a key immune process called autophagy with interferon gamma (IFN-γ) could help clear a lethal bacterial infection in cystic fibrosis, a new study suggests. The work, led by a team in The Research Institute at Nationwide ...
May 20, 2014
0
0
The increasing prevalence of diabetes worldwide has led to a rise in diabetic wounds, such as diabetic foot ulcers, which are challenging to treat and can result in amputation. Traditional treatments have limited effectiveness, ...
Mar 18, 2024
0
1
Researchers and students from Monash University and the University of Warwick have come together for the first time to share ideas, knowledge and expertise as part of a Monash Warwick Alliance seed funded autophagy workshop.
Nov 12, 2015
0
4
A cell contains many specialized subunits, called organelles, that carry out important tasks such as energy generation, protein synthesis, and calcium outflux. But what happens when something goes wrong with one of the organelles?
Aug 31, 2023
0
0
University of Rochester scientists have discovered a gene with a critical link to pancreatic cancer, and further investigation in mice shows that by blocking the gene's most important function, researchers can slow the disease ...
May 1, 2014
0
0
