Dietary restriction, or limited food intake without malnutrition, has beneficial effects on longevity in many species, including humans. A new study from the Sanford Burnham Prebys Medical Discovery Institute (SBP), published ...
Jul 14, 2016
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In order to live, it is necessary for creatures not only to synthesize essential components, but also degrade harmful or superfluous components. Autophagy, an intracellular degradation system conserved among eukaryotes from ...
Jul 11, 2016
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Researchers from the Duke-NUS Graduate Medical School Singapore (Duke-NUS) and Duke Medicine have identified a potential treatment strategy for an often-fatal inherited glycogen storage disease.
Nov 18, 2015
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Joslin researchers have uncovered the action of a gene that regulates the education of T cells, providing insight into how and why the immune system begins mistaking the body's own tissues for targets. The gene, Clec16a, ...
May 12, 2015
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Taking out the garbage is a crucial step in housecleaning. Similarly, autophagy is the body's first-line of defense against the buildup up of toxic substances, degrading old organelles and proteins to provide new substrates ...
Mar 26, 2015
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Neurodegenerative disorders such as Alzheimer's disease are typically characterized by protein deposits in the brain. These are comprised of defective, insoluble proteins which no longer fulfill their function and which cells ...
Feb 11, 2015
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The role of a phosphatase protein in promoting the self-destruction of healthy cells and the progression of ovarian cancer has been identified by A*STAR researchers. Known to be overexpressed in cancer cells, the protein, ...
Jan 21, 2015
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Bacillus Calmette-Guerin (BCG) is a vaccine widely used in low and middle-income countries to protect against childhood tuberculosis. Besides its specific anti-tuberculosis effects, BCG can also function as a general immune-booster, ...
Oct 30, 2014
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Researchers from Stanford University School of Medicine have discovered a link between a protective mechanism used by cells and the activation of muscle stem cells. Cells use autophagy to recycle cellular "building blocks" ...
Oct 14, 2014
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No matter what type of chemotherapy you attack a tumor with, many cancer cells resort to the same survival tactic: They start eating themselves.
Oct 9, 2014
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