Immunology
Patient-driven discovery reveals potential target for autoimmune diseases
A medical mystery served as the genesis for a Yale-led study that has promising implications for treating a range of autoimmune diseases.
Jul 16, 2024
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News tagged with b-cells
Diseases, Conditions, Syndromes
Scientists identify 'unconventional' new pathway for TB vaccines
An "unconventional" immune response now identified by scientists from the Hackensack Meridian Center for Discovery and Innovation (CDI) is a potential new pathway for developing new vaccines for tuberculosis (TB), according ...
Jul 15, 2024
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Neuroscience
New immune cell therapy benefits lab models of ALS and shows positive results in an individual with the disease
Immune system dysregulation and elevated inflammation contribute to the development of the fatal neurodegenerative condition amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.
Jul 11, 2024
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Oncology & Cancer
Trial of cell-based therapy for high-risk lymphoma leads to FDA breakthrough designation
CAR-T cell therapy, which targets a specific protein on the surface of cancer cells, causes tumors to shrink or disappear in about half of patients with large B-cell lymphoma who haven't experienced improvement with chemotherapy ...
Jul 10, 2024
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Diseases, Conditions, Syndromes
Hepatitis B: 'Sleep timer' for immune cells discovered
In chronic hepatitis B, the liver contains immune cells that could destroy hepatitis B virus infected cells but are inactive. A team from the Technical University of Munich (TUM) has discovered that cells in blood vessels ...
Jul 10, 2024
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Immunology
New pathway in immune defense discovered: Interaction of monocytes and platelets decoded
Monocytes, a special type of white blood cell, secrete cytokines as inflammatory messengers that are crucial for an appropriate immune response. Researchers at the University Hospital Bonn (UKB) and the University of Bonn ...
Jul 8, 2024
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Vaccination
Scientists discover PVP-037, a potent vaccine adjuvant
Many vaccines are only partially effective, have waning efficacy, or do not work well in the very young or the very old. For more than a decade, Ofer Levy, MD, Ph.D., and David Dowling, Ph.D., in the Precision Vaccines Program ...
Jul 3, 2024
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Diseases, Conditions, Syndromes
Research team identifies target protein regulating autoimmune disease lupus
A research team including Professor Yoontae Lee and Jiho Park, a Ph.D. candidate, from the Department of Life Sciences at Pohang University of Science and Technology (POSTECH) has discovered that a particular protein promotes ...
Jul 2, 2024
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Oncology & Cancer
Engineered plasma cells show long-lasting antileukemic activity in mice
Researchers show for the first time that engineered human plasma B cells can be used to treat a disease—specifically leukemia—in a humanized animal model. The results mark a key step in the realization of ePCs as therapies ...
Jul 2, 2024
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Immunology
Switching decisions: Interleukin-12 influences B cell immune response
B cells are known to generate antibodies through two different responses—an "emergency response" and an "everything is okay, let's prepare for the future response," says Mark Shlomchik, UPMC Professor and Distinguished ...
Jun 27, 2024
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