With more targeted therapies being approved each year for cancer, the development of drug resistance to these agents is a growing concern. It has often been assumed that drug resistance is due to the presence or development ...
May 15, 2019
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An international team of scientists has pinpointed the genetic drivers of diffuse large B-cell lymphoma—the most common type of blood cancer—and determined the genes' clinical significance. The study, published in the ...
Oct 31, 2017
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A group of researchers led by the Francis Crick Institute, working with the National Physical Laboratory (NPL) and Imperial College London, have discovered that breast cancer cells expressing a cancer-driving gene heavily ...
Nov 9, 2023
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Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health have identified a strong association between the product of a gene expressed in most cancers, including ...
Mar 13, 2023
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Tumors and certain viral infections pose a challenge to the human body which the immune system typically fails to handle. In these diseases it switches to a hypofunctional state that prevents adequate protection. However, ...
Jun 18, 2019
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Researchers at the National Eye Institute (NEI) have identified, isolated, and characterized a unique population of B cells that tamps down the immune system, reducing chronic inflammation. Infusions of purified IL-27 regulatory ...
Dec 2, 2021
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Researchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) have used CRISPR/Cas9 technology to engineer donor T cells to try to treat seriously ill ...
Oct 27, 2022
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A new clinical study on COVID-19 launched late last month by a University at Buffalo researcher is investigating why the novel coronavirus is so potentially devastating for adults but barely causes a reaction in most children.
Apr 7, 2020
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Australian scientists have confirmed a 'weak link' in the immune system – identifying the exact conditions under which an infection can trigger an autoantibody response, a process not clearly understood until now.
Nov 9, 2012
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A multi-institutional national study has identified unique molecular features responsible for the development and progression of metastatic breast cancer. One of the key features involves changes in the immune system that ...
Jan 9, 2023
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