Genetics

Epigenetic changes drive the fate of a B cell

B cells are the immune cells responsible for creating antibodies, and most B cells, known as B2 cells, produce antibodies in response to a pathogen or a vaccine, providing defense and immunity against infections. But a small ...

Diseases, Conditions, Syndromes

How B cells fight the COVID-19 virus

A study of antibody-producing B cells from patients who recovered from COVID-19 reveals a new cross-reactive antibody and what makes some B cells more effective at neutralizing the virus.

Medical research

Less is more for the next generation of CAR T cells

When researchers from Penn Medicine found that many patients with B-cell acute lymphoblastic leukemia (ALL) treated with the investigational chimeric antigen receptor (CAR) T cell therapy targeting the CD22 antigen didn't ...

Diseases, Conditions, Syndromes

Hepatitis B: What people can learn from donkeys

The discovery of a previously unknown hepatitis B virus in donkeys and zebras opens up new opportunities for understanding the course of the disease. A global research consortium was able to show that the course of the infection ...

Diseases, Conditions, Syndromes

What happens to immunity levels post COVID-19 infection?

Australian scientists have described the evolution of immunity levels up to four months following COVID-19 infection, finding that while antibody levels drop dramatically in the first one to two months, the decrease then ...

Diseases, Conditions, Syndromes

Genetics may play role in determining immunity to COVID-19

Neutralizing antibodies develop within two weeks of a SARS-CoV-2 infection, but their durability and intensity can vary by individual, prompting concerns about the prospects of long-lasting immunity and efficacy of COVID-19 ...

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