When antibody-producing immune cells encounter infectious pathogens for the first time, they engage a signal cascade to generate a massive activation signal within seconds. The mechanisms underlying this acute initial activation ...
Nov 5, 2020
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The brain is uniquely protected against invading bacteria and viruses, but its defence mechanism has long remained a mystery. Now, a study in mice, confirmed in human samples, has shown that the brain has a surprising ally ...
Nov 4, 2020
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Immunotherapies, such as checkpoint inhibitor drugs, have made worlds of difference for the treatment of cancer. Most clinicians and scientists understand these drugs to act on what's known as the adaptive immune system, ...
Oct 29, 2020
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167
The gut is an unusually noisy place, where hundreds of species of bacteria live alongside whatever microbes happen to have hitched a ride in on your lunch. Scientists have long suspected that the gut's immune system, in the ...
Oct 29, 2020
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WEHI researchers have used powerful 'single cell multi-omics' technologies to discover a previously unknown ancestor of T and B lymphocytes, which are critical components of our immune system.
Oct 19, 2020
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As scientists around the world develop life-saving COVID-19 vaccines and therapies, many are still wondering exactly why the disease proves deadly in some people and mild in others.
Oct 6, 2020
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Researchers at The University of Texas MD Anderson Cancer Center have identified molecular and cellular characteristics of anti-CD19 CAR T cell infusion products associated with how patients with large B-cell lymphoma (LBCL) ...
Oct 5, 2020
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Our immune system can efficiently fend off viral diseases. T-cells can directly destroy virus-infected cells and enable the formation of efficient, virus-neutralizing antibodies by B-cells. These two cell types also play ...
Oct 1, 2020
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112
New research has uncovered the previously unknown presence of CD19—a B cell molecule targeted by chimeric antigen receptor (CAR) T cell immunotherapy to treat leukemia, lymphoma, and multiple myeloma—in brain cells that ...
Sep 21, 2020
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86
Flu season comes around like clockwork every year, and sooner or later everyone gets infected. The annual flu shot is a key part of public health efforts to control the flu, but the vaccine's effectiveness is notoriously ...
Aug 31, 2020
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