The hormone secreting islets of Langerhans in the pancreas have a unique cyto-architecture that allows functional interrelationships between the different cell types. Somatostatin is secreted by the delta cell and is an effective ...
Aug 16, 2019
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131
Alzheimer's disease, the most common cause of dementia among the elderly, is characterized by plaques and tangles in the brain, with most efforts at finding a cure focused on these abnormal structures. But a University of ...
Aug 12, 2019
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801
Beta-amyloid plaques, the protein aggregates that form in the brains of Alzheimer's patients, disrupt many brain functions and can kill neurons. They can also damage the blood-brain barrier—the normally tight border that ...
Aug 12, 2019
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3
In a new study, Yale researchers challenge a long-held assumption about how insulin-producing cells in the pancreas sense and respond to glucose. Their findings could lead to changes in the way that scientists approach the ...
Jul 18, 2019
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A Joslin Diabetes Center study among people treated for type 1 diabetes for many years has discovered that a minority may have monogenic diabetes, a non-autoimmune inherited condition that in some cases does not require insulin ...
Jul 2, 2019
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1
Years before symptoms of Alzheimer's disease appear, two kinds of damaging proteins silently collect in the brain: amyloid beta and tau. Clumps of amyloid accumulate first, but tau is particularly noxious. Wherever tangles ...
Jun 24, 2019
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The primary cause of the loss of functionality in transplanted pancreatic islets is their low capacity to create new vessels to transport nutrients. Researchers from the University of Barcelona and IDIBAPS have led a study ...
Jun 20, 2019
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1
Immune checkpoint inhibitors (ICIs) are an emerging type of cancer immunotherapy that uses the immune system to attack cancer cells. However, in some patients they cause the immune system to attack healthy cells, leading ...
Jun 11, 2019
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4
A treatment affecting the immune system effectively slowed the progression to clinical type 1 diabetes in high risk individuals, according to findings from National Institutes of Health-funded research. The study is the first ...
Jun 10, 2019
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98
Research from Joslin Diabetes Center has shown in mice that insulin resistance increases the proportion of aged beta-cells which are dysfunction. Such an increase in aged beta-cells could lead to type 2 diabetes. These researchers ...
May 30, 2019
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